Alesse, Demulen, Ortho-cyclen, Seasonale, TriPhasil, Yasmin and others


Synthetic and semi-synthetic analogs of estrogen and/or progesterone used to prevent pregnancy by (1) inhibiting ovulation and/or (2) thickening cervical mucus (3) diminishing endometrial integrity.

Drug-Induced Nutrient Depletions
  • Vitamin B6
  • Folic acid
  • Magnesium
Symptoms of Depletion

Folic Acid

  • Megaloblastic anemia
  • Birth defects
  • Cervical dysplasia
  • Elevated homocysteine
  • Headache
  • Fatigue
  • Hair loss
  • Increased infections


  • Muscle cramps
  • Weakness
  • Insomnia
  • Loss of appetite
  • GI disorders
  • Kidney stones
  • Osteoporosis
  • Nervousness
  • Restlessness
  • Depression
  • Anxiety
  • Confusion
  • Fatigue
  • High blood pressure

Vitamin B6

  • Depression
  • Low energy


Alpha Base Multivitamin
Additional Supplementation

Folic Acid

Dietary Supplements that have Potential for Interactions with Drug (or Drug Class)**

St. John’s Wort and Garlic:
St. John’s Wort and garlic supplements may decrease the effectiveness of oral contraceptives. Women taking St. John’s Wort and/or garlic supplements along with oral contraceptives should use an additional form of birth control. St. John’s Wort also causes photosensitivity which may be exacerbated by oral contraceptives.

Green Tea Catechins:
Use caution with green tea and oral contraceptives. Oral contraceptives can decrease caffeine clearance by 40–65% and may increase adverse effects of caffeine in green tea. Adjust dose or discontinue if necessary.

Iron and Copper:
Oral contraceptives may increase serum iron and copper levels.

*Suggested supplements that may support overall health and are not at all intended to replace any prescription medications.

**These supplements listed may have the potential to interact with the drug or drug class. Use caution or avoid these supplements unless approved by your physician or preferred health care provider.