ACE Inhibitors, Angiotensin Receptor Blockers (ARBs), Calcium Channel Blockers, Beta Blockers, Diuretics
The major classes of anti-hypertensive drugs are beta blockers, calcium channel blockers, ACE inhibitors, angiotensin receptor blockers, and thiazide diuretics. These drugs work to reduce blood pressure by decreasing total peripheral resistance or by reducing cardiac output, or both.
ACE Inhibitors cause an increased excretion of zinc.
Beta Blockers depletion may be due to the inhibition of two CoQ-10 enzymes succinoxidase and NADH-oxidase; these actions could depress myocardial function.